Radioactive Iodine Remnant Ablation: The Beta-knife Completion Thyroidectomy
نویسندگان
چکیده
The rationale and objectives for radioactive iodine (RAI) ablation remain perplexing to many. This review addresses the meaning, clinical context and the goals of "ablation": the RAI treatment after a total thyroidectomy. This article also aims to clarify the definition of a total thyroidectomy and how a thyroid remnant can introduce a confounding factor in the postoperative management of patients with differentiated thyroid cancer. The implications of an existing thyroid remnant on RAI diagnostic imaging and serum thyroglobulin levels are discussed. This review provides a rational approach validating the utility of RAI remnant ablation regardless of the patient's risk stratification.
منابع مشابه
The advantage of total thyroidectomy to avoid reoperation for incidental thyroid cancer in multinodular goiter.
HYPOTHESIS To investigate the impact of total thyroidectomy on the rate of completion thyroidectomy for incidentally found thyroid cancer in euthyroid multinodular goiter. DESIGN A randomized, prospective clinical trial. SETTING A tertiary referral center. PATIENTS Patients with euthyroid multinodular goiter without any preoperative suspicion of malignancy, history of familial thyroid can...
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OBJECTIVE Remnant ablation with radioactive iodine (I-131) is a successful form of treatment that aims to destroy the remaining residual tissue and/or metastatic tissue after total thyroidectomy in differentiated thyroid cancer (DTC) patients. High level of thyroid stimulating hormone (TSH) (≥30 mIU/L) is recommended for success of ablation treatment. In this retrospective study, our aim was to...
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Differentiated thyroid carcinomas are typically treated with total thyroidectomy as initial therapy. Subsequent radioactive iodine (RAI) ablation destroys post-surgical thyroid remnants, can additionally provide adjuvant therapy of residual and metastatic thyroid cancers, and enhances the sensitivity and specificity of further diagnostic studies. There is current controversy regarding whether a...
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BACKGROUND Radioactive iodine (I-131) is routinely used for the treatment of differentiated thyroid cancer following surgery. Drug-induced liver injury (DILI) is a leading cause of acute liver failure. Here we reported a rare case of diffuse hepatic uptake (DHU) of radioactive iodine (I-131) induced hepatotoxicity in patient with I-131 ablation therapy after thyroidectomy. CASE PRESENTATION A...
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